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How and why vibrio cholerae got its bend

How and why vibrio cholerae got its bend

von Thomas Fester | Mrz 2, 2017 | Biochemistry, Molecular Cytology, Molecular Medicine, News

The curves of Vibrio cholerae Vibrio cholerae, the causative agent of cholera has a characteristic curved shape. How is this shape achieved and what is it good for? To answer this question Bartlett and colleagues looked for mutant strains unable to form curved rods....
About rings and strings: novel principles in the organization of chromatin

About rings and strings: novel principles in the organization of chromatin

von Thomas Fester | Mrz 2, 2017 | Biochemistry, Molecular Structures, News

The complexity of storing, distributing and accessing DNA Each single nucleus of our body cells contains 46 DNA-molecules with a total length of about 2 meters. These extremely long molecules not only have to be packaged to fit into the small nuclei. They have to be...
Step by step – the assembly of complex I

Step by step – the assembly of complex I

von Thomas Fester | Mrz 2, 2017 | Biochemistry, Molecular Structures, News

Oxyhydrogen is the fuel of our bodies‘ cells If there is one chemical reaction providing the basis for our eukaryotic, multicellular life style, it is the oxyhydrogen reaction. Two very simple reactants, oxygen and hydrogen are reacting to form a similar simple...
An ATP-sensitive Potassium Channel

An ATP-sensitive Potassium Channel

von Thomas Fester | Feb 4, 2017 | Biochemistry, Molecular Structures, News

Biochemistry The structure of a pancreatic K+-channel has been elucidated using Cryo-EM. The core channel (upper gif) consists of four identical subunits and is given in full colour, with each subunit in a different colour. A regulatory subunit (lighter colour) is...
How do plants produce Casparian strips?

How do plants produce Casparian strips?

von Thomas Fester | Feb 3, 2017 | Biochemistry, Molecular Cytology, News

Importance of the endodermis in root transport processes The outer, absorptive and metabolic part of a root is separated from its central transportation unit (the central cylinder) by a tight border: the endodermis. This layer of cells has wax-like substances embedded...
Proteasomes are important elements in plant defense

Proteasomes are important elements in plant defense

von Thomas Fester | Jan 13, 2017 | Biochemistry, News

Proteasomes and plant defense Plants are challenged by a large variety of pathogens and therefore have acquired a complex, multi-layered system of defense. Üstün and colleagues have discovered a new, unexpected component of this defense system: the proteasome. The...
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