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About rings and strings: novel principles in the organization of chromatin

About rings and strings: novel principles in the organization of chromatin

von Thomas Fester | Mrz 2, 2017 | Biochemistry, Molecular Structures, News

The complexity of storing, distributing and accessing DNA Each single nucleus of our body cells contains 46 DNA-molecules with a total length of about 2 meters. These extremely long molecules not only have to be packaged to fit into the small nuclei. They have to be...
Step by step – the assembly of complex I

Step by step – the assembly of complex I

von Thomas Fester | Mrz 2, 2017 | Biochemistry, Molecular Structures, News

Oxyhydrogen is the fuel of our bodies‘ cells If there is one chemical reaction providing the basis for our eukaryotic, multicellular life style, it is the oxyhydrogen reaction. Two very simple reactants, oxygen and hydrogen are reacting to form a similar simple...
An ATP-sensitive Potassium Channel

An ATP-sensitive Potassium Channel

von Thomas Fester | Feb 4, 2017 | Biochemistry, Molecular Structures, News

Biochemistry The structure of a pancreatic K+-channel has been elucidated using Cryo-EM. The core channel (upper gif) consists of four identical subunits and is given in full colour, with each subunit in a different colour. A regulatory subunit (lighter colour) is...
Cannabinoid receptor CB1 from humans

Cannabinoid receptor CB1 from humans

von Thomas Fester | Dez 10, 2016 | Biochemistry, Molecular Structures, Neurobiology, News

Biochemistry Tetrahydrocannabinol from hashish is effective in humans, since it activates a receptor designed for hormon-like substances of the human body – endocannabinoids. These endocannabinoids address several receptors. Here we are talking only about their...
Structure and function of a protein complex facilitating the final steps in mRNA export from the nucleus

Structure and function of a protein complex facilitating the final steps in mRNA export from the nucleus

von Thomas Fester | Dez 9, 2016 | Molecular Cytology, Molecular Structures, News

Source: Fernandez-Martinez et al., Cell 167, 1215 – 1228 Scivit News – Visual Science More illustrations from Scivit More videos from Scivit Have a video abstract based on this cartoon (300 Euro) ← Previous News Further News...
A new perspective on the ER

A new perspective on the ER

von Thomas Fester | Nov 24, 2016 | Biochemistry, Molecular Cytology, Molecular Medicine, Molecular Structures, News

ER-sheets: lost in superresolution microscopy In german language people see things „with new eyes“, when they adopt a new perspective and this is precisely what just happened to the ER. Nixon-Abell and co-workers used a whole array of...
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