Mitochondrial cristae and ATPase

ATPase Dimers

von | Aug 18, 2016 | Molecular Structures, News | 1 Kommentar

Mitochondrial ATPases are able to form V-shaped dimers inducing a strong membrane curvature, ultimately leading to the formation of mitochondrial cristae. A recent publication from Hahn an collaegues closely analyzed the interacting subunits in the yeast Yarrowia lipolytica using X-ray crystallography and Cryo-EM. The illustration above shows some mitochondrial cristae (red colour) dotted with ATPases (yellow and blue colour). ATPase dimers, located at the cristae edges, are given in lighter colours.